Immunopharmacological Activities of Luteolin in Chronic Diseases

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초록

Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits (e.g., anti-inflammatory and anti-tumor functions). Luteolin (3 ', 4 ', 5,7-tetrahydroxyflavone) is a flavonoid found in vegetables, fruits, flowers, and herbs, including celery, broccoli, green pepper, navel oranges, dandelion, peppermint, and rosemary. Luteolin has multiple useful effects, especially in regulating inflammation-related symptoms and diseases. In this paper, we summarize the studies about the immunopharmacological activity of luteolin on anti-inflammatory, anti-cardiovascular, anti-cancerous, and anti-neurodegenerative diseases published since 2018 and available in PubMed or Google Scholar. In this review, we also introduce some additional formulations of luteolin to improve its solubility and bioavailability.

키워드

luteolinflavonoidchronic diseasecancerbioinformatics analysisin vivoin vitroNETWORK PHARMACOLOGYDIETARY LUTEOLINCANCER CELLSLUNG INJURYIN-VITROINFLAMMATIONAPOPTOSISPATHWAYBIOAVAILABILITYMACROPHAGES
제목
Immunopharmacological Activities of Luteolin in Chronic Diseases
저자
Huang, LeiKim, Mi-YeonCho, Jae Youl
DOI
10.3390/ijms24032136
발행일
2023-02
유형
Review
저널명
International Journal of Molecular Sciences
24
3