Construction of antibacterial electrospun nanofiber from poly(styrene-co-sulfadiazine) via electrospinning

Hwang, S.-H.; Ahn, K.-H.; Cha, H.; Kim, J.-Y.; Hwang, H.-G.; Huh, W.; Lee, S.

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Construction of antibacterial electrospun nanofiber from poly(styrene-co-sulfadiazine) via electrospinning

Hwang, S.-H.;
Ahn, K.-H.;
Cha, H.;
Kim, J.-Y.;
Hwang, H.-G.;
... Huh, W.;
... Lee, S.

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초록

In this study, sulfadiazine acrylamide monomer was synthesized by the reaction of sulfadiazine, known as an antibiotic substance, with acryloyl chloride. The monomer was characterized by 1 H-NMR, and 13 C-NMR. Using the synthesized sulfadiazine acrylamide monomer and styrene monomer, a copolymer, poly(styrene-co-sulfadiazine), was obtained by the free radical copolymerization and characterized by 1 H-NMR, GPC, DSC and TGA. The copolymer nanofibers web has been successfully prepared by electrospinning technique under DMF solution. The diameter of the nanofibers was in the range between 500 and 800 nm. Antibacterial activity of the nanofiber web was evaluated utilizing the colony counting method against Staphylococcus aureus and Escherichia coli.

키워드

Antibiotics; Electrospinning; Nanofiber; Poly(styrene-co-sulfadiazine); Sulfadiazine

제목: Construction of antibacterial electrospun nanofiber from poly(styrene-co-sulfadiazine) via electrospinning

저자: Hwang, S.-H.; Ahn, K.-H.; Cha, H.; Kim, J.-Y.; Hwang, H.-G.; Huh, W.; Lee, S.

발행일: 2009

유형: Article

저널명: 공업화학

권: 20

호: 4

페이지: 386 ~ 390