Exact Partition Function Zeros of The Wako-Saito-Munoz-Eaton Protein Model

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초록

I compute exact partition function zeros of the Wako-Saito-Munoz-Eaton model for various secondary structural elements and for two proteins, 1BBL and 1I6C, by using both analytic and numerical methods. Two-state and barrierless downhill folding transitions can be distinguished by a gap in the distribution of zeros at the positive real axis.

키워드

NONEQUILIBRIUM PHASE-TRANSITIONS; STATISTICAL-MECHANICAL MODEL; 1ST-ORDER TRANSITIONS; FOLDING MECHANISMS; 2-STATE PROTEINS; ENERGY LANDSCAPE; CONTINUUM SYSTEM; DOWNHILL; KINETICS; COOPERATIVITY
제목
Exact Partition Function Zeros of The Wako-Saito-Munoz-Eaton Protein Model
저자
Lee, Julian
DOI
10.1103/PhysRevLett.110.248101
발행일
2013-06-11
유형
Article
저널명
Physical Review Letters
권
110
호
24