Synthesis and Thermo-responsive Properties of Amino Group Terminated Poly(N-isopropylacrylamide) and Sodium Alginate-g-Poly(N-isopropylacrylamide)

초록

Amino group-terminated poly(N-isopropylacrylamide) (PNIPAAm-NH2) was synthesized via a radical polymerization of N-isopropylacrylamide (NIPAAm) using 2-aminoethanethiol hydrochloride (AESH) as a chain transfer agent. The molecular weight of the PNIPAAm-NH2 was controlled by changing the concentration of AESH. The LCST of the aqueous solution of PNIPAAm-NH2 increased slightly with increasing the AESH concentration. Alginate-g-PNIPAAm copolymer was synthesized by grafting PNIPAAm-NH2 onto sodium alginate using N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide and N-hydroxysuccinimide. The formation of the grafted copolymers was confirmed by Flirt spectroscopy, solubility in water, and SEM-EDS. Alginate-g-PNIPAAm also exhibited swelling-deswelling behavior. However, it showed a LCST at a slightly increased temperature compared to PNIPAAm. The swelling ratio of the alginate-g-PNIPAAm hydrogel increased with the increase of the grafted PNIPAAm content.

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