Fabrication of nanopatterned surfaces for tissue engineering

  • Jeong, E.J.; 
  • Lee, J.W.; 
  • Yeon, S.-J.; 
  • Lee, J.-W.; 
  • Kwark, Y.-J.; 
  • 외 4명

초록

The surface nanotopography of polymer substrates is a critical factor to regulate cellular behavior in tissue engineering approaches. In this study, nanopatterned surfaces were generated via self-assembly of polystyrene-b- poly(ethylene oxide)/dodecylbenzenesulfonic acid complex systems to control preosteoblast phenotype in vitro. Polystyrene domain sizes under 100 nm strongly affected the adhesion, proliferation, and differentiation of preosteoblasts cultured on the surfaces, irrespective of the same center-to-center distance between the domains. This approach may provide a useful means to design and develop novel polymer substrates for tissue engineering applications. © 2012 IEEE.

제목
Fabrication of nanopatterned surfaces for tissue engineering
저자
Jeong, E.J.; Lee, J.W.; Yeon, S.-J.; Lee, J.-W.; Kwark, Y.-J.; Rhee, S.-H.; Park, W.H.; Kim, S.H.; Lee, K.Y.
DOI
10.1109/iCBEB.2012.220
발행일
2012
학회명
2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012
개최지
Macau
학회 개최일
2012-05-28 ~ 2012-05-30